Liaoning Provincial People’s Hospital Successfully Performs Deep Cervical Lymphatic-Venous Anastomosis for Alzheimer’s Treatment
Recently, the Neurosurgery Center at Liaoning Provincial People’s Hospital achieved a significant milestone. A medical team successfully performed a deep cervical lymphatic-venous anastomosis on a patient with Alzheimer’s disease. This breakthrough offers new hope for patients and marks the first such procedure in the field of neurosurgery in Liaoning Province.
The patient, a 51-year-old individual, had experienced noticeable memory decline over the past three years, including difficulty recognizing family members, loss of communication skills, and increased irritability. After a thorough multidisciplinary evaluation involving PET-MRI and cerebrospinal fluid tests, the patient was diagnosed with Alzheimer’s disease.


The medical team opted for deep cervical lymphatic-venous anastomosis, an innovative treatment approach. After careful planning, the surgery was completed successfully. The patient showed significant cognitive improvement the following day, including the ability to recognize and name family members, and was discharged within a week. Follow-up reports indicated improved mood, communication skills, and daily living abilities.
Alzheimer’s disease is a neurodegenerative disorder characterized by progressive cognitive decline, with increasing prevalence among younger populations. Traditional treatments targeting amyloid-beta (Aβ) and tau protein deposits have shown limited effectiveness. Recent research highlights the role of impaired brain lymphatic drainage in Alzheimer’s pathology, where reduced cerebrospinal fluid clearance leads to Aβ and tau accumulation, accelerating neuronal damage. Deep cervical lymphatic-venous anastomosis, a novel surgical technique, creates a bypass between cervical lymphatics and veins to enhance metabolic waste clearance, offering a promising therapeutic avenue.
The procedure requires high-precision microsurgery under advanced microscopy, where lymphatic vessels are meticulously connected to veins to improve cerebral lymphatic circulation. This technique minimizes trauma and bleeding, ensuring faster recovery. Its success demands exceptional surgical skill.
This achievement represents a major advancement in neurodegenerative disease treatment in Liaoning Province, bringing new hope to Alzheimer’s patients and their families. The hospital remains committed to advancing research and treatment in this field.