The State Administration for Market Regulation has approved and released the recommended national standard “General Technical Requirements for Vascular Chips.” The standard will officially come into effect on May 1, 2027, marking significant progress in the construction of the organ chip standard system.
The vascular system is the core channel for drug delivery and disease progression. Vascular chips use microfluidic technology to construct three-dimensional vascular networks in vitro, dynamically simulating physiological processes such as vascular perfusion, barrier function, and biochemical metabolism. They have become a new type of production tool in fields such as innovative drug development, toxicological evaluation, and biomanufacturing.
The “General Technical Requirements for Vascular Chips” mainly specifies three aspects. First, it defines the terminology of vascular chips, establishing a unified cognitive benchmark for the industry. Second, it sets standards for chip appearance, cell sources, component performance, and biological performance, clarifying key evaluation indicators such as biocompatibility, tissue morphology, barrier function, cell activity, and functional characterization. Third, it outlines detection methods for corresponding indicators such as light transmittance, sealing, and working temperature tolerance, providing operational guidance for quality evaluation.
This standard forms technical synergy with the previously released national standard “General Technical Requirements for Skin Chips,” jointly promoting the construction of the multi-organ chip standard system. The implementation of this standard will help overcome species differences in animal experiments, promote the transition of vascular chip technology from scattered exploration to standardized application, and provide unified support for the design, research and development, manufacturing, and quality evaluation of vascular chips, thereby advancing the application of this technology in fields such as drug screening, toxicological evaluation, food safety, cosmetic safety, medical device evaluation, and environmental health risk assessment.
China
China is a vast East Asian country with one of the world’s oldest continuous civilizations, dating back over 4,000 years. Its rich history includes the rise and fall of dynasties such as the Qin, Tang, and Ming, as well as the construction of iconic landmarks like the Great Wall and the Forbidden City. Today, China blends ancient traditions with rapid modernization, making it a unique cultural and historical destination.
Great Wall
The Great Wall of China is a historic fortification stretching over 13,000 miles, built primarily between the 7th century BC and the 16th century AD to protect Chinese states and empires from invasions by nomadic groups like the Mongols. It was constructed using various materials, including stone, brick, and earth, with many sections rebuilt and reinforced during the Ming Dynasty (1368–1644). Today, it stands as a UNESCO World Heritage site and one of the most iconic symbols of China’s ancient engineering and cultural resilience.
Forbidden City
The Forbidden City, located in the heart of Beijing, China, served as the imperial palace for 24 emperors during the Ming and Qing dynasties from 1420 to 1912. Construction began in 1406 under Emperor Yongle, and the complex is renowned for its vast scale, traditional Chinese architecture, and deep cultural significance. Today, it is a UNESCO World Heritage site and houses the Palace Museum, showcasing centuries of Chinese art and history.
Great Wall
The Great Wall of China is a series of ancient fortifications built across northern China to protect Chinese states and empires from invasions and raids. Construction began as early as the 7th century BC, with the most famous sections built during the Ming Dynasty (1368–1644). Stretching over 13,000 miles, it is now a UNESCO World Heritage site and one of the most iconic symbols of China.
Forbidden City
The Forbidden City, located in the heart of Beijing, China, served as the imperial palace for 24 emperors during the Ming and Qing dynasties from 1420 to 1912. Construction began in 1406 under Emperor Yongle, and it functioned as the political and ceremonial center of Chinese government for nearly 500 years. Today, it is a UNESCO World Heritage site and houses the Palace Museum, showcasing vast collections of ancient Chinese art and artifacts.
